Delta oscillations phase limit neural activity during sevoflurane anesthesia

摘要

Schematic of the study protocol and data from an illustrative subject. We acquired data using a randomized, cross-over study design. Anesthetic-drugs were administered for approximately 45 min. , End-tidal sevoflurane concentration, behavioral response probability curve, and corresponding frontal electroencephalogram spectrogram during the sevoflurane study visit. , End-tidal sevoflurane concentration, behavioral response probability curve, and corresponding frontal electroencephalogram spectrogram during the sevoflurane-plus-ketamine study visit. Shaded regions represent the 95% confidence bounds. Sevo sevoflurane, Ket Ketamine