The long noncoding RNA PCGEM1 promotes cell proliferation migration and invasion via targeting the miR-182/FBXW11 axis in cervical cancer

摘要

PCGEM1 is highly expressed in CC tissues and predicts poor prognosis. The expression of PCGEM1 in 68 pairs of CC and normal cervical tissues was determined by qRT-PCR. Kaplan–Meier survival curves and log-rank tests were used to assess the relationship between PCGEM1 levels and overall survival time of CC patients. The median of PCGEM1 expression levels in CC tissues was taken as cutoff. PCGEM1 levels in four CC cells, including C33A, HeLa, SiHa, and CaSki, and Ect1/E6E7 cells (normal human cervix epithelial cells) were analyzed by qRT-PCR