Intralesional steroid injections to prevent refractory strictures in patients with oesophageal atresia: study protocol for an international multicentre randomised controlled trial (STEPS-EA trial)

摘要

Anastomotic stricture formation is the most common postoperative complication after oesophageal atresia (OA) repair. The standard of care is endoscopic dilatation. A possible adjuvant treatment is intralesional steroid injection, which is thought to inhibit scar tissue formation and thereby to prevent stricture recurrence. We hypothesise that this intervention could prevent refractory strictures and reduce the total number of dilatations needed in these children.