The impact of Clonorchis sinensis infection on immune response in mice with type II collagen-induced arthritis

摘要

Mice infected with metacercariae. metacercariae were collected from fish and examination by microscope.  + CIA group. Histological of liver tissues from -infected mice stained with hematoxylin and eosin (H&E). Histological structure of liver was destroyed. Massive inflammatory cells infiltrated around the portal area accompanied by collagen hyperplasia and cholangiocyte proliferation. , CIA group and Control group. Histological of liver tissues from the CIA and control group mice stained with hematoxylin and eosin (H&E). In both the CIA and control group, the histological structure of liver in mice was normal, without inflammatory cell infiltration and collagen hyperplasia