Levofloxacin-ceftazidime administration regimens combat Pseudomonas aeruginosa in the hollow-fiber infection model simulating abnormal renal function in critically ill patients

摘要

Various PK simulations in the study. T , elimination half-life; AUC , area under the concentration-curve from time 0 to 24 h; C , maximum drug concentration; C , minimum drug concentration; T > MIC is the percentage of administration interval. concentration-time curve of LVF 500mg qd 60min inf; : concentration-time curve of CAZ 1g q8h 30min inf