From methylglyoxal to pyruvate: a genome-wide study for the identification of glyoxalases and D-lactate dehydrogenases in Sorghum bicolor

摘要

Schematic representation of the glyoxalase pathway for methylglyoxal detoxification in plants. Methylglyoxal (MG) is converted to S-D-lactoylglutathione (SLG) by glyoxalase I (GLYI) enzyme which is then converted to D-lactate by glyoxalase II (GLYII). Glutathione is used in the first reaction catalysed by GLYI but is recycled in the second reaction catalysed by GLYII. D-lactate is further metabolized to pyruvate through D-lactate dehydrogenase (D-LDH) enzyme which passes electrons to cytochrome C (CYTc)