SWIFTCORE: a tool for the context-specific reconstruction of genome-scale metabolic networks

摘要

(COBRA) is the current state-of-the-art in the genome-scale metabolic network modelling [ ]. COBRA methods systematize biochemical constraints into a mathematical framework which synthetic biologists can utilize to quantitatively simulate metabolic pathways in order to answer the relevant biological questions. There is a critical mass of studies that combine these curated high-dimensional models and analysis for drug discovery or many other applications [ – ].