Evolution of metabolic capabilities and molecular features of diplonemids kinetoplastids and euglenids

摘要

Gains and losses of metabolic functions in the evolution of Euglenozoa. The maximum-likelihood phylogenetic tree of Euglenozoa is based on a concatenated alignment of 20 conserved proteins (see the “ ” section). Nodes with 100% bootstrap support and posterior probability of 1.0 are marked with black circles. The tree was rooted with the sequences of a heterolobosean . Kinetoplastids, diplonemids, and euglenids are shown on blue, red, and green background, respectively. The scale bar denotes the number of substitutions per site. Diplonemids and kinetoplastids represent sister clades with the maximal posterior probability and bootstrap support. Gains and losses of KEGG Orthology (KO) identifiers falling into the category “Metabolism” were mapped onto the phylogenetic tree using the Dollo parsimony algorithm implemented in the Count software v.10.4. Gains and losses are depicted on gray background in blue and vermillion, respectively. For each node of interest, KEGG Orthology categories with the highest number of lost KOs are shown