Insulin Glucose Insulin Resistance and Incident Colorectal Cancer in Male Smokers

摘要

Background & AimsHyperinsulinemia is a putative colorectal cancer (CRC) risk factor. Insulin resistance (IR) commonly precedes hyperinsulinemia and can be quantitatively measured using the homeostasis model assessment-insulin resistance (HOMA-IR) index. To date, few studies have directly examined serum insulin as an indicator of CRC risk and none have reported associations based on HOMA-IR.