Evidence of Absence or Absence of Evidence? A Re-analysis of the Effects of Low-Dose Aspirin in IVF

摘要

ObjectiveTo assess the conflicting evidence whether low-dose aspirin (LDA) is beneficial in in-vitro fertilization (IVF), and evaluate the meta-analysis performed by Gelbaya et al. in the March 2007 issue of Human Reproduction Update, in which they found no effects of LDA and recommended discontinuing its use in IVF. We present a re-analysis of the effects of LDA in IVF and raise methodological questions regarding the analysis by Gelbaya et al.