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A Multicenter Randomized Double-Blind Placebo-Controlled Trial of Oral Type I Collagen Treatment in Patients With Diffuse Cutaneous Systemic Sclerosis

机译：弥漫性皮肤系统性硬化症患者口服I型胶原蛋白治疗的多中心随机双盲安慰剂对照试验

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ObjectiveTo investigate the safety and efficacy of oral bovine type I collagen (CI) treatment in patients who have had diffuse cutaneous systemic sclerosis (dc-SSc; scleroderma) for ≤10 years.

机译：目的探讨口服牛I型胶原（CI）治疗弥漫性皮肤系统性硬化（dc-SSc；硬皮病）≤10年的患者的安全性和有效性。

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Arnold E. Postlethwaite; Weng Kee Wong; Philip Clements; Soumya Chatterjee; Barri J. Fessler; Andrew H. Kang; Joseph Korn; Maureen Mayes; Peter A. Merkel; Jerry A. Molitor; Larry Moreland; Naomi Rothfield; Robert W. Simms; Edwin A. Smith; Robert Spiera; Virginia Steen; Kenneth Warrington; Barbara White; Frederick Wigley; Daniel E. Furst;
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年(卷),期 -1(58),6
年度 -1
页码 1810–1822
总页数 22
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专利

1. A multicenter, randomized, double-blind, placebo-controlled trial of oral type I collagen treatment in patients with diffuse cutaneous systemic sclerosis: I. oral type I collagen does not improve skin in all patients, but may improve skin in late-phase disease. [J] . Postlethwaite AE, Wong WK, Clements P, Arthritis and Rheumatism . 2008,第6期

机译：口服I型胶原蛋白治疗弥漫性皮肤系统硬化患者的多中心，随机，双盲，安慰剂对照试验：I.口服I型胶原蛋白并不能改善所有患者的皮肤，但可能会改善晚期疾病的皮肤。
2. A randomised, double-blind, placebo-controlled trial: Intravenous immunoglobulin treatment in patients with diffuse cutaneous systemic sclerosis [J] . TakeharaK., IhnH., SatoS. Clinical and experimental rheumatology . 2013,第Suppla76期

机译：一项随机，双盲，安慰剂对照试验：弥漫性皮肤系统性硬化症患者的静脉内免疫球蛋白治疗
3. Riociguat in patients with early diffuse cutaneous systemic sclerosis (RISE-SSc): randomised, double-blind, placebo-controlled multicentre trial [J] . Khanna Dinesh, Allanore Yannick, Denton Christopher P., Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2020,第5期

机译：早期弥漫性皮肤系统硬化症患者的RIOCIGUAT（崛起-SC）：随机，双盲，安慰剂控制的多元试验
4. MULTI-CENTER, PLACEBO-CONTROLLED, DOUBLE-BLIND, RANDOMIZED STUDY OF ORAL TOCERANIB PHOSPHATE (PALLADIATM, SU11654), A RECEPTOR TYROSINE KINASE INHIBITOR, FOR THE TREATMENT OF DOGS WITH RECURRENT MAS [C] . Cheryl L London, Carolyn J Henry, Anthony W Rusk, Annual conference of the Veterinary Cancer Society . 2008

机译：多中心，安慰剂对照，双盲，随机研究口服Toceranib磷酸盐（Palladia TM，SU11654），受体酪氨酸激酶抑制剂，用于治疗经常性MAS的狗
5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
6. A Randomized Double-Blind Placebo-Controlled Trial of Recombinant Human Relaxin in the Treatment of Systemic Sclerosis with Diffuse Scleroderma [O] . Dinesh Khanna, Philip J. Clements, Daniel E. Furst, -1

机译：一项随机双盲安慰剂对照的重组人类松弛的试验系统性硬化症治疗弥漫性硬皮病
7. Faculty Opinions recommendation of Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial. [O] . Heidi Jacobe 2021

机译：教师意见建议ABATACEPT在早期弥漫性皮肤系统硬化症中：II期调查员启动的结果，多中心，双盲，随机，安慰剂对照试验。

A Multicenter Randomized Double-Blind Placebo-Controlled Trial of Oral Type I Collagen Treatment in Patients With Diffuse Cutaneous Systemic Sclerosis

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