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An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1-related disease in children

机译：年龄依赖性的甘露糖结合凝集素2基因变异与儿童HIV-1相关疾病的关系

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摘要

BackgroundMannose-binding lectin (MBL) is part of the lectin pathway of complement activation against various pathogens; however, its role in innate immune responses against HIV-1 infection in children is unknown.

机译：背景甘露糖结合凝集素（MBL）是针对各种病原体的补体激活的凝集素途径的一部分。但是，其在儿童针对HIV-1感染的先天免疫应答中的作用尚不清楚。

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期刊名称 other
作者
Kumud K. Singh; Alexis Lieser; Ping K. Ruan; Terry Fenton; Stephen A. Spector;
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作者单位

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年(卷),期 -1(122),1
年度 -1
页码 e2
总页数 19
原文格式 PDF
正文语种
中图分类
关键词
Mannose binding lectin-2 polymorphisms HIV-1 disease central nervous system impairment children;

机译：甘露糖结合凝集素2;多态性;HIV-1疾病;中枢神经系统损害;儿童;

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专利

1. Association of genetic variants of mannan-binding (MBL) lectin-2 gene, MBL levels and function in ulcerative colitis and Crohn's disease [J] . SivaramG., TiwariS.K., BardiaA., Innate immunity . 2011,第6期

机译：甘露聚糖结合（MBL）凝集素2基因的遗传变异，溃疡性结肠炎和克罗恩病中MBL水平和功能的关联
2. Genetic variants in the host restriction factor APOBEC3G are associated with HIV-1-related disease progression and central nervous system impairment in children [J] . SinghK.K., WangY., GrayK.P., JAIDS: Journal of acquired immune deficiency syndromes . 2013,第2期

机译：宿主限制因子APOBEC3G的遗传变异与儿童的HIV-1相关疾病进展和中枢神经系统损伤有关
3. Genetic polymorphism of the mannose-binding protein gene in children with sickle cell disease: identification of three new variant alleles and relationship to infections. [J] . Neonato MG, Lu CY, Guilloud Bataille-M, European journal of human genetics: EJHG . 1999,第6期

机译：镰状细胞病患儿甘露糖结合蛋白基因的遗传多态性：鉴定三个新的变异等位基因及其与感染的关系。
4. Medical Big Data Analysis System to Discover Associations between Genetic Variants and Diseases [C] . Daehee Kim, Stephanie Gamboa, Vanessa Hernandez, IEEE International Conference on Communications . 2021

机译：医疗大数据分析系统发现遗传变异与疾病之间的关联
5. Utilizing rare and X-linked variants for inference of population size history and association studies of complex diseases. [D] . Gao, Feng. 2017

机译：利用稀有和X连锁的变体推论人口规模历史和复杂疾病的关联研究。
6. Association Study of Mannose-Binding Lectin Levels and Genetic Variants in Lectin Pathway Proteins with Susceptibility to Age-Related Macular Degeneration: A Case-Control Study [O] . Michael Osthoff, Melinda M. Dean, Paul N. Baird, -1

机译：甘露糖结合凝集素水平和凝集素通路蛋白遗传变异与年龄相关性黄斑变性易感性的关联研究：病例对照研究
7. An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1–related disease in children [O] . Kumud K. Singh, Alexis Lieser, Ping K. Ruan, 2008

机译：儿童HIV-1相关疾病的甘露结合凝集素-2遗传变异的年龄依赖性依赖性

An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1-related disease in children

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