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Ranking USRDS provider specific SMRs from 1998-2001

机译:1998-2001年USRDS提供商特定SMR排名

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摘要

Provider profiling (ranking/percentiling) is prevalent in health services research. Bayesian models coupled with optimizing a loss function provide an effective framework for computing non-standard inferences such as ranks. Inferences depend on the posterior distribution and should be guided by inferential goals. However, even optimal methods might not lead to definitive results and ranks should be accompanied by valid uncertainty assessments. We outline the Bayesian approach and use estimated Standardized Mortality Ratios (SMRs) in 1998-2001 from the United States Renal Data System (USRDS) as a platform to identify issues and demonstrate approaches. Our analyses extend by computing estimates developed by that minimize errors in classifying providers above or below a percentile cut-point, by combining evidence over multiple years via a first-order, autoregressive model on log(SMR), and by use of a nonparametric prior. Results show that ranks/percentiles based on maximum likelihood estimates of the SMRs and those based on testing whether an SMR = 1 substantially under-perform the optimal estimates. Combining evidence over the four years using the autoregressive model reduces uncertainty, improving performance over percentiles based on only one year. Furthermore, percentiles based on posterior probabilities of exceeding a properly chosen SMR threshold are essentially identical to those produced by minimizing classification loss. Uncertainty measures effectively calibrate performance, showing that considerable uncertainty remains even when using optimal methods. Findings highlight the importance of using loss function guided percentiles and the necessity of accompanying estimates with uncertainty assessments.
机译:提供者配置文件(排名/百分比)在健康服务研究中很普遍。贝叶斯模型与优化损失函数相结合,为计算非标准推断(例如等级)提供了有效的框架。推论取决于后验分布,并应以推论目标为指导。但是,即使是最佳方法也可能无法得出确定的结果,并且应该在等级上伴随有效的不确定性评估。我们概述了贝叶斯方法,并使用1998年至2001年美国肾脏数据系统(USRDS)估计的标准死亡率(SMR)作为识别问题和演示方法的平台。我们的分析通过计算估计值来扩展,该估计值通过将对数年间的证据通过对数(SMR)进行的一阶自回归模型进行组合,并使用非参数先验来最小化将提供者的分类在百分比以上或以下的误差最小化。 。结果表明,基于SMR的最大似然估计的等级/百分率以及基于测试SMR = 1是否显着低于最佳估计的等级/百分率。使用自回归模型结合四年来的证据减少了不确定性,与仅基于一年的百分位数相比,提高了性能。此外,基于超过适当选择的SMR阈值的后验概率的百分位数基本上与通过最小化分类损失产生的百分位数相同。不确定性度量有效地校准了性能,表明即使使用最佳方法,仍然存在相当多的不确定性。调查结果突出显示了使用损失函数指导的百分位数的重要性以及不确定性评估中随附估计的必要性。

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