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Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts

机译：蛋白酶激活受体（PAR）-2活化会影响人骨关节炎骨骨质细胞的骨吸收性能

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IntroductionIn osteoarthritis (OA), the subchondral bone undergoes a remodelling process involving several factors synthesized by osteoblasts. In this study, we investigated the expression, production, modulation, and role of PAR-2 in human OA subchondral bone osteoblasts.

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期刊名称 other
作者
Nathalie Amiable; Steeve Kwan Tat; Daniel Lajeunesse; Nicolas Duval; Jean-Pierre Pelletier; Johanne Martel-Pelletier; Christelle Boileau;
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年(卷),期 -1(44),6
年度 -1
页码 1143–1150
总页数 20
原文格式 PDF
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中图分类
关键词
Inflammation Bone Osteoblasts Molecular pathways Modelling and remodelling;

机译：炎症;骨骼;成骨细胞;分子途径;建模和重塑;

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1. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. [J] . Amiable N, Tat SK, Lajeunesse D Bone . 2009 ,第6期

机译：蛋白酶激活受体（PAR）-2激活影响人骨关节炎软骨下骨成骨细胞的骨吸收特性。
2. The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells. [J] . Kwan-Tat S, Pelletier JP, Lajeunesse D, Clinical and experimental rheumatology . 2008 ,第2期

机译：骨保护素（OPG）和核因子κB配体（RANKL）受体激活剂在人骨关节炎软骨下成骨细胞中的差异表达是这些疾病细胞代谢状态的指标。
3. Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts. [J] . Kwan-Tat S, Pelletier JP, Amiable N, Arthritis and Rheumatism . 2008 ,第12期

机译：EphB4受体通过其特异性配体ephrin B2在人骨关节炎软骨下骨成骨细胞中的激活。
4. Osteoarthritic changes in cartilage and subchondral bone [C] . Perepezko E., Kalscheur V., Checovich M., Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint . 2002

机译：软骨和软骨下骨的骨关节炎变化
5. Ultrasound Parameters for Human Osteoarthritic Subchondral Bone Ex Vivo: Comparison with Micro-Computed Tomography Parameters [D] . Kiyan, Wataru 2019

机译：人骨关节炎软骨下骨的超声参数：与微计算机断层扫描参数的比较。
6. The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor κB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells [O] . Steeve Kwan Tat, Jean-Pierre Pelletier, Daniel Lajeunesse, -1

机译：人骨关节炎软骨下骨成骨细胞中骨保护素（OPG）和核因子κB受体激活剂（RANKL）的差异表达是这些疾病细胞代谢状态的指标
7. 14 PROTEINASE-ACTIVATED RECEPTOR (PAR)-2 IN OSTEOARTHRITIC SUBCHONDRAL BONE OSTEOBLASTS: IDENTIFICATION OF A NEW THERAPEUTIC TARGET [O] . Amiable N., KwanTat S., Martel-Pelletier J., 2007

机译：14骨关节炎性软骨下骨成骨细胞中蛋白酶激活的受体（PAR）-2：鉴定新的治疗靶点

Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts

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