Palladium-Catalyzed Hydroalkylation of Styrenes with Organozinc Reagents to Form Carbon-Carbon sp3-sp3 Bonds under Oxidative Conditions

摘要

An unconventional route for the formation of sp³-sp³ C-C bonds from various styrene and an organozinc reagents in a formal alkene hydroalkylation process is detailed. Mechanistically this process is proposed to proceed by initial transmetallation followed formation of a Pd-H which is subsequently trapped with the styrene.