Alarms for Continuous Glucose Monitors: Hypoglycemia Prediction with Subject-Specific Recursive Time-Series Models

摘要

BackgroundAvoiding hypoglycemia while keeping glucose within the narrow normoglycemic range (70–120 mg/dl) is a major challenge for patients with type 1 diabetes. Continuous glucose monitors can provide hypoglycemic alarms when the measured glucose decreases below a threshold. However, a better approach is to provide an early alarm that predicts a hypoglycemic episode before it occurs, allowing enough time for the patient to take the necessary precaution to avoid hypoglycemia.