Processing of lexical verbs involves automatic access to argument structure entries entailed within the verb's representation. Recent neuroimaging studies with young normal listeners suggest that this involves bilateral posterior perisylvian tissue, with graded activation in these regions based on argument structure complexity. The aim of the present study was to examine the neural mechanisms of verb processing using functional magnetic resonance imaging (fMRI) in older normal volunteers and patients with stroke-induced agrammatic aphasia, a syndrome in which verb, as compared to noun, production often is selectively impaired, but verb comprehension in both on-line and off-line tasks is spared. Fourteen healthy listeners and five age-matched aphasic patients performed a lexical decision task, which examined verb processing by argument structure complexity, i.e., one-argument (i.e., intransitive (v1)); two-argument (i.e., transitive (v2)), and three-argument (v3) verbs. Results for the age-matched listeners largely replicated those for younger participants studied by : v3-v1 comparisons showed activation of the angular gyrus in both hemispheres and this same heteromodal region was activated in the left hemisphere in the (v2+v3)-v1 contrast. Similar results were derived for the agrammatic aphasic patients, however, activation was unilateral (in the right hemisphere for 3 participants) rather than bilateral likely because these patients' lesions extended to the left temporoparietal region. All performed the task with high accuracy and, despite differences in lesion site and extent, they recruited spared tissue in the same regions as healthy normals. Consistent with psycholinguistic models of sentence processing, these findings indicate that the posterior language network is engaged for processing verb argument structure and is crucial for semantic integration of argument structure information.
展开▼
机译:转换术语± Sup> [n i Sub>] f(+/-) min sup>的条件最小化结构的逻辑动态过程的方法Sub> AND ± Sup> [m i Sub>] f(+/-) min Sub>在功能添加结构中± Sup> f < Sub> 1 Sub>(Σ RU Sub>) min Sub>,不带纹波f 1 Sub>(± Sup>←←)和循环ΔtΣ Sub>→5∙f(&)-和5个条件逻辑函数f(&)-,并通过三元数系统的算术公理同时转换术语参数的过程f RU Sub>(+ 1,0,-1)及其实现其的功能结构(俄罗斯逻辑版本)