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Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage

机译：协调癌症种系抗原启动子和卵巢癌中的全球DNA低甲基化：与硼砂/ CTCF表达比和高级阶段相关联

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PurposeCancer germline (CG) antigens are frequently expressed and hypomethylated in epithelial ovarian cancer (EOC), but the relationship of this phenomenon to global DNA hypomethylation is unknown. In addition, the potential mechanisms leading to DNA hypomethylation, and its clinicopathological significance in EOC, have not been determined.

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期刊名称 other
作者
Anna Woloszynska-Read; Wa Zhang; Jihnhee Yu; Petra A. Link; Paulette Mhawech-Fauceglia; Golda Collamat; Stacey N. Akers; Kelly R. Ostler; Lucy A. Godley; Kunle Odunsi; Adam R. Karpf;
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年(卷),期 -1(17),8
年度 -1
页码 2170–2180
总页数 17
原文格式 PDF
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DNA methylation DNA hypomethylation cancer germline antigens cancer testis antigens ovarian cancer;

机译：DNA甲基化;DNA低甲基化;癌症种系抗原;癌症睾丸抗原;卵巢癌;

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专利

1. Coordinated Cancer Germline Antigen Promoter and Global DNA Hypomethylation in Ovarian Cancer: Association with the BORIS/CTCF Expression Ratio and Advanced Stage. [J] . Woloszynska Read A, Zhang W, Yu J, Clinical cancer research: an official journal of the American Association for Cancer Research . 2011,第8期

机译：卵巢癌中协调一致的癌症生殖细胞抗原启动子和整体DNA甲基化不足：与BORIS / CTCF表达比和晚期相关。
2. BORIS/CTCFL expression is insufficientfor cancer-germline antigen gene expression and DNA hypomethylationin ovarian cell lines [J] . Adam R. Karpf, Anna Woloszynska-Read, Boquan Jin, Cancer immunity . 2010,第2010期

机译：BORIS / CTCFL表达不足以表达卵巢癌细胞系中的癌胚抗原基因表达和DNA次甲基化
3. Evaluation of folate receptor 1 ( FOLR1 ) mRNA expression, its specific promoter methylation and global DNA hypomethylation in type I and type II ovarian cancers [J] . Sara Notaro, Daniel Reimer, Heidi Fiegl, BMC Cancer . 2016,第1期

机译：在I型和II型卵巢癌中评估叶酸受体1（FOLR1）mRNA的表达，其特异性启动子甲基化和整体DNA甲基化不足
4. Integration of gene expression, genome wide DNA methylation, and gene networks for clinical outcome prediction in ovarian cancer [C] . Lin Zhang, Hui Liu, Jia Meng, IEEE International Conference on Bioinformatics and Biomedicine . 2013

机译：整合基因表达，全基因组DNA甲基化和基因网络以预测卵巢癌的临床结果
5. Genomic and epigenomic characterization of global DNA hypomethylation in human epithelial ovarian cancer [D] . Zhang, Wa. 2014

机译：人类上皮性卵巢癌中整体DNA低甲基化的基因组和表观基因组学表征
6. BORIS/CTCFL expression is insufficientfor cancer-germline antigen gene expression and DNA hypomethylationin ovarian cell lines [O] . Anna Woloszynska-Read, Smitha R. James, Chajoun Song, 2010

机译：BORIS / CTCFL表达不足用于癌症生殖细胞抗原基因表达和DNA低甲基化在卵巢细胞系中
7. Coordinated Cancer Germline Antigen Promoter and Global DNA Hypomethylation in Ovarian Cancer: Association with the BORIS/CTCF Expression Ratio and Advanced Stage [O] . Anna Woloszynska-Read, Wa Zhang, Jihnhee Yu, 2011

机译：协调癌症种系抗原启动子和卵巢癌中的全球DNA低甲基化：与硼砂/ CTCF表达比和高级阶段相关联

Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage

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