Time to Discontinuation of First- and Second-Generation Antipsychotic Medications in the Treatment of Schizophrenia

摘要

BackgroundContinuous adherence to antipsychotic treatment is critical for individuals with schizophrenia to benefit optimally, yet studies have shown rates of antipsychotic discontinuation to be high with few differences across medications. We investigated discontinuation of selected first- and second-generation antipsychotics among individuals with schizophrenia receiving usual care in a VA healthcare network in the U.S. midatlantic region.