Genomewide Association between GLCCI1 and Response to Glucocorticoid Therapy in Asthma

摘要

BACKGROUNDThe response to treatment for asthma is characterized by wide interindividual variability, with a significant number of patients who have no response. We hypothesized that a genomewide association study would reveal novel pharmacogenetic determinants of the response to inhaled glucocorticoids.