Sub-optimal CD4 T-lymphocyte responses among HIV infected patients who develop TB during the first year of ART.

摘要

Study backgroundPoor CD4 T-lymphocyte responses to anti-retroviral treatment (ART) are associated with increased HIV disease progression and mortality. In sub-Saharan Africa a substantial proportion of HIV infected patients are co-infected with TB. This study evaluated the effect of active TB presenting after ART initiation on immunological responses to ART.