Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production A Randomized Controlled Trial

摘要

ContextSteroid 5α-reductase inhibitors are used to treat benign prostatic hyperplasia and androgenic alopecia, but the role of 5α-dihydrotestosterone (DHT) in mediating testosterone’s effects on muscle, sexual function, erythropoiesis, and other androgen-dependent processes remains poorly understood.