Quantification of concordance and discordance between apolipoprotein-B and the currently recommended non-HDL-Cholesterol goals for cardiovascular risk assessment in patients with diabetes and hypertriglyceridemia

摘要

AimsIn patients with diabetes and hypertriglyceridemia, LDL-cholesterol (LDL-C) provides an inaccurate reflection of LDL particle burden. The relative value of non-HDL-cholesterol (non-HDL-C) and apolipoprotein- B (Apo-B) in estimating cardiovascular risk is controversial. We assessed the discordance between non-HDL-C and Apo- B targets in patients with diabetes with TG 200–499 mg/dl.