SOCIAL DOMINANCE IN FEMALE MONKEYS: DOPAMINE RECEPTOR FUNCTION AND COCAINE REINFORCEMENT

摘要

BackgroundBrain imaging and behavioral studies suggest an inverse relationship between dopamine (DA) D2/D3 receptors and vulnerability to cocaine abuse, though most research has utilized males. For example, male monkeys that become dominant in a social group have significant elevations in D2/D3 receptor availability and are less vulnerable to cocaine reinforcement.