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Nebivolol does not protect against 5/6 ablation/infarction induced chronic kidney disease in rats - comparison with angiotensin II receptor blockade

机译：Nebivolol在大鼠中不受5/6消融/梗死诱导的慢性肾病 - 与血管紧张素II受体封闭的比较

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AimsNitric oxide (NO) deficiency contributes to chronic kidney disease progression. Nebivolol, a beta adrenergic receptor antagonist, may enhance endogenous NO. Here, we investigated whether nebivolol attenuates hypertension and renal injury after 5/6 ablation/ infarction (A/I). Efficacy was compared to the AT1 receptor antagonist olmesartan.

机译：目标氧化物（NO）缺乏有助于慢性肾病进展。 β肾上腺素能受体拮抗剂痣可以增强内源性No。在这里，我们研究了在5/6消融/梗死后痣衰减高血压和肾损伤（A / I）。将疗效与AT1受体拮抗剂Olmesartan进行比较。

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期刊名称 other
作者
Jennifer M. Sasser; Natasha C. Moningka; Tatsiana Tsarova; Chris Baylis;
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作者单位

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年(卷),期 -1(91),1-2
年度 -1
页码 54–63
总页数 28
原文格式 PDF
正文语种
中图分类
关键词
Olmesartan glomerular sclerosis nitric oxide proteinuria hypertension;

机译：奥美沙坦;肾小球硬化;一氧化氮;蛋白尿;高血压;

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专利

1. Nebivolol does not protect against 5/6 ablation/infarction induced chronic kidney disease in rats - Comparison with angiotensin II receptor blockade [J] . SasserJ.M., MoningkaN.C., TsarovaT., Life sciences . 2012,第1a2期

机译：奈必洛尔不能预防5/6消融/梗塞诱发的大鼠慢性肾脏疾病-与血管紧张素II受体阻滞剂的比较
2. Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney diseasen in the rat: a comparison with angiotensin II receptor blockade [J] . Chris Baylis Nephrology Dialysis Transplantation . 2012,第3期

机译：奈必洛尔对大鼠慢性一氧化氮合酶抑制性高血压和慢性肾脏疾病的保护作用：与血管紧张素Ⅱ受体阻断剂的比较
3. Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney disease in the rat: a comparison with angiotensin II receptor blockade. [J] . Natasha C Moningka, Tatsiana Tsarova, Jennifer M Sasser, Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association . 2012,第3期

机译：奈必洛尔对大鼠慢性一氧化氮合酶抑制性高血压和慢性肾脏疾病的保护作用：与血管紧张素II受体阻滞剂的比较。
4. Attenuation of Myocardial Stunning by Angiotensin II Type 1 Receptor Blockade with Candesartan: Role of the Type 2 Receptor [C] . B.I. Jugdutt, V. Mcnon International Congress on Coronary Artery Disease . 2003

机译：血管紧张素II型1受体封闭因子的抗心肌壮丽的衰减：2型受体的作用
5. The effect of angiotensin II receptor blockade, prior to, during and after a myocardial infarction in rats with and without insulin resistance. [D] . Pourdjabbar, Ali. 2005

机译：在有或没有胰岛素抵抗的大鼠中，在心肌梗塞之前，之中和之后，血管紧张素II受体阻滞的作用。
6. Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney disease in the rat: a comparison with angiotensin II receptor blockade [O] . Natasha C. Moningka, Tatsiana Tsarova, Jennifer M. Sasser, -1

机译：奈必洛尔对大鼠慢性一氧化氮合酶抑制性高血压和慢性肾脏疾病的保护作用：与血管紧张素Ⅱ受体阻断剂的比较
7. Nebivolol does not protect against 5/6 ablation/infarction induced chronic kidney disease in rats — Comparison with angiotensin II receptor blockade [O] . Departments of Physiology and Functional Genomics, University of Florida, Gainesville, FL, USA ( host institution ), Sasser, Jennifer M. ( UF author ), Moningka, Natasha C. ( UF author ), 2012

机译：奈必洛尔不能预防5/6消融/梗塞诱发的大鼠慢性肾脏疾病—与血管紧张素II受体阻滞剂的比较

Nebivolol does not protect against 5/6 ablation/infarction induced chronic kidney disease in rats - comparison with angiotensin II receptor blockade

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