Frequency and Trajectory of Abnormalities in Respiratory Rate Temperature and Oxygen Saturation in Severe Pneumonia in Children

摘要

The frequency or trajectory of vital sign abnormalities in children with pneumonia has not been described. In a cohort of 2,714 patients with severe pneumonia identified and treated as per the World Health Organization definition and recommendations, tachypnea, fever and hypoxia were found in 68.9%, 23.6% and 15.5% of children, respectively. Median oxygen saturation returned to a normal range by 10 hours following initiation of treatment, followed by temperature at 12 hours and respiratory rate at 22 hours for subjects less than 12 months and at 48 hours for those greater than or equal to 12 months of age.