Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood

摘要

IntroductionmicroRNA (miRNA) are small non-coding RNA species that are transcriptionally processed in the host cell and released extracellularly into the bloodstream. Normally involved in post-transcriptional gene silencing, the deregulation of miRNA has been shown to influence pathogenesis of a number of diseases.