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Diastolic Dysfunction of Aging Is Independent of Myocardial Structure but Associated with Plasma Advanced Glycation End-Product Levels

机译：老化心肌结构是独立的但与相关血浆糖化终产物水平的舒张功能不全

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BackgroundHeart failure is associated with abnormalities of myocardial structure, and plasma levels of the advanced glycation end-product (AGE) N^ε-(carboxymethyl)lysine (CML) correlate with the severity and prognosis of heart failure. Aging is associated with diastolic dysfunction and increased risk of heart failure, and we investigated the hypothesis that diastolic dysfunction of aging humans is associated with altered myocardial structure and plasma AGE levels.

机译：背景心力衰竭与心肌结构异常有关，晚期糖基化终产物（AGE）N ^{ε-（羧甲基）赖氨酸（CML）的血浆水平与心力衰竭的严重程度和预后相关。衰老与舒张功能障碍和心力衰竭风险增加相关，我们研究了这样的假说，即衰老的人的舒张功能障碍与心肌结构和血浆AGE水平的改变有关。}

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期刊名称 other
作者
Duncan J. Campbell; Jithendra B. Somaratne; Alicia J. Jenkins; David L. Prior; Michael Yii; James F. Kenny; Andrew E. Newcomb; Casper G. Schalkwijk; Mary Jane Black; Darren J. Kelly;
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年(卷),期 -1(7),11
年度 -1
页码 e49813
总页数 14
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1. Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction. [J] . Hartog JW, van de Wal RM, Schalkwijk CG, European journal of heart failure: journal of the Working Group on Heart Failure of the European Society of Cardiology . 2010 ,第4期

机译：高血压和舒张功能障碍患者的晚期糖基化终产物，抗高血压治疗和舒张功能。
2. Acute effects of statin on reduction of angiopoietin-like 2 and glyceraldehyde-derived advanced glycation end-products levels in patients with acute myocardial infarction: a message from SAMIT (Statin for Acute Myocardial Infarction Trial) [J] . Shimomura Mitsuhiro, Oyama Jun-ichi, Takeuchi Masayoshi, Heart and vessels: An international journal . 2016 ,第10期

机译：他汀类药物对急性心肌梗死患者减少血管生成素样2和甘油醛衍生的晚期糖基化终产物水平的急性作用：来自SAMIT的消息（他汀类药物用于急性心肌梗死试验）
3. Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolicn dysfunction [J] . Adriaan A. Voors European Journal of Heart Failure . 2010 ,第4期

机译：高血压和舒张功能障碍患者的晚期糖基化终产物，抗高血压治疗和舒张功能
4. ANTIBODY-FREE LC-MS METHODS FOR LOW TO SUB NG/ML QUANTIFICATION OF THE SOLUBLE RECEPTOR OF ADVANCED GLYCATION END-PRODUCTS (sRAGE) IN SERUM [C] . Frank Klont, Simon D. Pouwels, Marrit Hadderingh, International Mass Spectrometry Conference . 2018

机译：用于低至亚Ng / ml定量的无抗体的LC-MS方法，血清中晚期糖糖末端产物（SRAGE）的可溶性受体的定量
5. Influence of Four Differently Processed Diets on Plasma Levels of Advanced Glycation End Products (Ages), Serum Levels of Receptor for Advanced Glycation End Products (Rage), Serum and Urine Metabolome, and Fecal Microbiome in Healthy Dogs [D] . ?Bridglalsingh, Siobhan 2020

机译：四种不同加工饮食对晚期糖糖末端产物（年龄），晚期糖糖末端产物（RAGE），血清和尿液代谢的血清受体水平的影响，以及健康犬的粪便微生物组
6. Influence of high glucose and advanced glycation end-products (ages) levels in human osteoblast-like cells gene expression [O] . Cristina Miranda, Mercè Giner, M. José Montoya, 2016

机译：高糖和晚期糖基化终产物（年龄）水平对人成骨样细胞基因表达的影响
7. Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels. [O] . Duncan J Campbell, Jithendra B Somaratne, Alicia J Jenkins, 2012

机译：衰老的舒张功能障碍与心肌结构无关，但与血浆晚期糖基化终产物水平有关。

Diastolic Dysfunction of Aging Is Independent of Myocardial Structure but Associated with Plasma Advanced Glycation End-Product Levels

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