首页> 外国专利> DECOMPOSING AGENT FOR ADVANCED GLYCATION END PRODUCT, AND COSMETIC CONTAINING THE DECOMPOSING AGENT FOR ADVANCED GLYCATION END-PRODUCT

DECOMPOSING AGENT FOR ADVANCED GLYCATION END PRODUCT, AND COSMETIC CONTAINING THE DECOMPOSING AGENT FOR ADVANCED GLYCATION END-PRODUCT

机译:高级糖化终产物的分解剂,化妆品中包含高级糖化终产物的分解剂

摘要

PROBLEM TO BE SOLVED: To elucidate the body of an active ingredient which bears decomposing actions of advanced glycation end-products AGEs in an extract from a plant body of Artemisia princeps Pamp. of the family Compositae, and to thereby stably maintain the decomposing actions of the AGEs.;SOLUTION: A compound having the following properties is used as an index substance: (1) having λmax's at 405-415 nm and 660-670 nm; (2) having an H-NMR spectrum; (3) having a C-NMR spectrum; (4) exhibiting a single peak at about 15 min in HPLC analysis under the following conditions: mobile phase: 90% acetonitrile, column: ODS 4.6×250 mm, flow velocity: 1 mL/min, temperature: 40°C, and detection: 210 nm in an ultraviolet part; and (5) chemical compositional formula: C34H40O9, and mass analysis spectrum: 593 (M+H).;COPYRIGHT: (C)2010,JPO&INPIT
机译:要解决的问题:阐明一种有效成分,该成分具有从蒿蒿植物体内提取物中的高级糖基化终产物AGEs分解的作用。解决方案:具有以下性质的化合物用作指标物质:(1)在405-415 nm和660-670 nm处具有λmax。 ; (2)具有1 H-NMR光谱。 (3)具有C-NMR光谱。 (4)在以下条件下,在HPLC分析中在约15分钟处显示一个峰:流动相:90%乙腈,柱:ODS 4.6×250mm,流速:1mL / min,温度:40℃,和检测:紫外线部分为210 nm; (5)化学组成式:C 34 H 40 O 9 ,质量分析光谱:593(M + H)。 :(C)2010,JPO&INPIT

著录项

  • 公开/公告号JP2010070468A

    专利类型

  • 公开/公告日2010-04-02

    原文格式PDF

  • 申请/专利权人 POLA CHEM IND INC;

    申请/专利号JP20080237059

  • 发明设计人 KANAMARU AKIKO;TADA AKIHIRO;

    申请日2008-09-16

  • 分类号C07G99/00;A61K8/97;A61K36/28;A61K36/00;A61Q19/08;A61P17/00;A61P43/00;

  • 国家 JP

  • 入库时间 2022-08-21 19:03:09

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