Mephedrone and Methylenedioxypyrovalerone (MDPV) Major Constituents of Bath Salts Produce Opposite Effects at the Human Dopamine Transporter

摘要

RationalePsychoactive ‘bath salts’ represents a relatively new drug of abuse combination that was placed in Schedule I in October 2011. Two common ingredients of ‘bath salts’ include the cathinone analogs: mephedrone and methylenedioxy-pyrovalerone (MDPV). The mechanism of action of these synthetic cathinone analogs has not been well investigated.