RHD VARIANTS IN POLISH BLOOD DONORS ROUTINELY TYPED AS D NEGATIVE

摘要

BACKGROUNDBlood donors exhibiting a weak D or DEL phenotypical expression may be mistyped D negative by standard serology hence permitting incompatible transfusion to D negative recipients.Molecular methods may overcome these technical limits. Our aim was to estimate the frequency of RHD alleles among the apparently D negative Polish donor population and to characterize its molecular background.