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Thymic Stromal Lymphopoietin Is Up-Regulated in the Skin of Patients With Systemic Sclerosis and Induces Profibrotic Genes and Intracellular Signaling That Overlap With Those Induced by Interleukin-13 and Transforming Growth Factor β

机译:胸腺基质淋巴细胞生成素在系统性硬化症患者的皮肤中上调并诱导纤维化基因和细胞内信号传导与白介素13和转化生长因子β诱导的重叠

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摘要

ObjectiveTo explore the expression of thymic stromal lymphopoietin (TSLP) in patients with diffuse cutaneous systemic sclerosis (dcSSc) and compare its effects in vivo and in vitro with those of interleukin-13 (IL-13) and transforming growth factor β (TGFβ).
机译:目的探讨胸腺基质淋巴细胞生成素(TSLP)在弥漫性皮肤系统性硬化症(dcSSc)患者中的表达,并比较其与白介素-13(IL-13)和转化生长因子β(TGFβ)在体内和体外的作用。

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