Resting Heart Rate and Risk of Sudden Cardiac Death in the General Population: Influence of Left Ventricular Systolic Dysfunction and Heart Rate-Modulating Drugs

摘要

BackgroundHigher levels of resting heart rate (HR) have been associated with sudden cardiac death (SCD) but mechanisms are poorly understood. We hypothesized that severe left ventricular systolic dysfunction (LVSD) and rate-modulating drugs explain the HR-SCD relationship.