Prevention of Airway Allograft Tolerance by Poly (I:C) Requires Type-I Interferon Responsiveness for Mouse Airway Obliteration

摘要

BACKGROUNDRespiratory RNA viruses are associated with bronchiolitis obliterans syndrome (BOS) in lung transplant recipients (LTRS), however the immune mechanisms that regulate airway obliteration remain incompletely understood.