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Multiple listing for pediatric heart transplantation in the USA: Analysis of OPTN registry data from 1995 through 2009

机译:美国小儿心脏移植的多重清单:1995年至2009年OPTN注册中心数据的分析

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摘要

Multiple listing is associated with shorter waitlist durations and increased likelihood of transplantation for renal candidates. Little is known about multiple listing in pediatric heart transplantation. We examined the prevalence and outcomes of multiple listing using OPTN data from 1995 through 2009. Characteristics and waitlist outcomes of propensity-score-matched single- and multiple-listed patients were compared. Multiple listing occurred in 23 of 6290 listings (0.4%). Median days between listings was 35 (0–1015) and median duration of multiple listings was 32 days (3–363). Among multiple-listed patients, there were trends toward less ECMO use (0% vs. 11%, p = 0.1) and more frequent requirement for a prospective cross-match (17% vs. 8%, p = 0.08). Multiple-listed patients more commonly had private insurance (78% vs. 56%; p = 0.03). Urgency status at listing was similar between groups (1/1A: 61% vs. 64%, 1B/2: 39 vs. 36%; p = 0.45) as were weight, age, diagnosis, ventilator/inotrope use, and median income (each p ≥ 0.17). There was a trend toward increased incidence of heart transplantation for multiple-listed patients at three, six, and 24 months (50%, 65%, 80%) vs. single-listed patients (40%, 54%, 64%; p = 0.11). Multiple listing for pediatric heart transplantation in the USA occurs infrequently and is more common in patients with private insurance.
机译:多次挂号与等待名单的持续时间较短和肾候选物移植的可能性增加有关。关于儿科心脏移植中的多个清单知之甚少。我们使用1995年至2009年的OPTN数据检查了多重上市的患病率和结局。比较了倾向得分匹配的单一和多重上市患者的特征和候补名单。在6290个房源中,有23个出现了多重上市(0.4%)。列表之间的中位数天数为35(0-1015),多次列表之间的中位数持续时间为32天(3-363)。在多名患者中,存在使用ECMO减少的趋势(0%比11%,p = 0.1),更频繁地进行前瞻性交叉匹配(17%vs. 8%,p = 0.08)。多名患者更常使用私人保险(78%比56%; p = 0.03)。组之间的紧急状态相似(1 / 1A:61%对64%,1B / 2:39对36%; p = 0.45),体重,年龄,诊断,使用呼吸机/尿道和中位数收入也是如此(每个p≥0.17)。在三,六个和24个月时(50%,65%,80%),与单例患者(40%,54%,64%)相比,多例患者的心脏移植发生率有增加的趋势。 = 0.11)。在美国,多次出现儿科心脏移植的情况很少见,在有私人保险的患者中更为常见。

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