Increased Risk of Developing Digestive Tract Cancer in Subjects Carrying the PLCE1 rs2274223 AG Polymorphism: Evidence from a Meta-Analysis

摘要

BackgroundTo date, the association between phospholipase C epsilon 1 (PLCE1) rs2274223 A>G and risk of digestive tract cancer (DTC) remains inconclusive. To derive a more precise estimation of the association, we conducted a meta-analysis on all eligible case–control studies involving 8281 cases and 10,532 controls.