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Low Grade Elastic Compression Regimen for Venous Leg Ulcers-An Effective Compromise for Patients Requiring Daily Dressing Changes

机译:低级弹性压迫疗法治疗下肢静脉溃疡-对需要每日换药的患者的有效折衷

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摘要

Venous leg ulcers affect millions of patients worldwide and are a tremendous financial burden on our healthcare system. The hallmark of venous disease of the lower extremities is venous hypertension, and compression is the current mainstay of treatment. However, many patients are noncompliant, in part because of the complexity of the dressings and the difficulties with application and removal. The aim of our study was to determine an effective compression dressing regimen for patients with venous leg ulcers who require changing the ulcer primary dressing twice daily. We used two layers of a latex free tubular elastic bandage for compression. The primary endpoint of our study was increased wound healing rate and our secondary endpoint was complete wound closure. All active study subjects had positive healing rates at week 4 and week 8. Two subjects achieved complete wound closure by week 8. We conclude that compression with a latex-free tubular elastic bandage can be safely used in patients with venous leg ulcers requiring frequent dressing changes. This type of compression allows for daily inspection of wounds, dressing changes at home, flexibility in the context of clinical trials, and is a compromise for patients that are intolerant to compression dressings.
机译:下肢静脉溃疡影响全球数百万患者,是我们医疗保健系统的巨大经济负担。下肢静脉疾病的标志是静脉高血压,而压迫是目前的治疗方法。然而,许多患者不顺从,部分原因是敷料的复杂性以及施用和去除的困难。我们研究的目的是为需要每天两次更换溃疡初次敷料的静脉曲张溃疡患者确定有效的加压敷料方案。我们使用两层无乳胶的管状弹性绷带进行压缩。我们研究的主要终点是伤口愈合速度的提高,而次要终点是伤口完全闭合。所有活跃的研究对象在第4周和第8周的治愈率均为阳性。两名患者在第8周实现了完全伤口闭合。我们得出的结论是,无乳胶的管状弹性绷带加压可以安全地用于需要经常换药的下肢静脉溃疡患者变化。这种压缩方式允许每天检查伤口,在家更换敷料,在临床试验中具有灵活性,并且是对不能承受压缩敷料的患者的折衷。

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