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Pro-Inflammatory Interleukin-1 Genotypes Potentiate the Risk of Coronary Artery Disease and Cardiovascular Events Mediated by Oxidized Phospholipids and Lipoprotein (a)

机译：促炎性白介素1基因型增强了由氧化的磷脂和脂蛋白介导的冠状动脉疾病和心血管事件的风险（a）

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摘要

ObjectiveTo assess the influence of pro-inflammatory IL-1 genotype status on the risk of CAD, defined as >50% diameter stenosis, and cardiovascular events mediated by OxPL and Lp(a).

机译：目的评估促炎性IL-1基因型状态对冠心病风险的影响，冠心病定义为直径狭窄> 50％，以及OxPL和Lp（a）介导的心血管事件。

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期刊名称 other
作者
Sotirios Tsimikas; Gordon W. Duff; Peter B. Berger; John Rogus; Kenneth Huttner; Paul Clopton; Emmanuel Brilakis; Kenneth S Kornman; Joseph L Witztum;
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作者单位

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年(卷),期 -1(63),17
年度 -1
页码 1724–1734
总页数 22
原文格式 PDF
正文语种
中图分类
关键词
lipoproteins oxidation atherosclerosis lipoprotein (a) oxidized phospholipids IL-1 polymorphism haplotype inflammation genetic risk stratification;

机译：脂蛋白;氧化;动脉粥样硬化;脂蛋白（a）;氧化磷脂;IL-1;多态性;单倍型;炎症;遗传风险分层;

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专利

1. Pro-inflammatory interleukin-1 genotypes potentiate the risk of coronary artery disease and cardiovascular events mediated by oxidized phospholipids and lipoprotein(a) [J] . TsimikasS., DuffG.W., BergerP.B., Journal of the American College of Cardiology . 2014,第17期

机译：促炎性白介素-1基因型增强了氧化磷脂和脂蛋白介导的冠状动脉疾病和心血管事件的风险（a）
2. Circulating Levels of Small Dense Low-Density Lipoprotein Cholesterol and Cardiovascular Event Risk in Patients With Stable Coronary Artery Disease Treated With High-versus Low-Dose Pitavastatin in the Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy With Pitavastatin in Coronary Artery Disease Trial [J] . Ishii Junnichi, Kashiwabara Kosuke, Takahashi Hiroshi, Circulation: An Official Journal of the American Heart Association . 2019,第25期

机译：用高冠状动脉疾病患者循环小密集低密度脂蛋白胆固醇和心血管事件风险，治疗高剂量低剂量岩浆对冠状动脉疾病试验岩浆汀类腐脱素治疗的随机评估
3. Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events. [J] . Tsimikas S, Brilakis ES, Lennon RJ, Journal of Lipid Research . 2007,第2期

机译：IgG和IgM自身抗体与氧化型低密度脂蛋白的关系与冠心病和心血管事件的关系。
4. Evaluation of Oxidized Low-Density Lipoprotein in the Coronary Circulation of Patients with Coronary Artery Disease, and its Association with Percutaneous Coronary Intervention [C] . M.M. Ramadan, M. Kodama, S. Hirono, International Congress on Coronary Artery Disease . 2007

机译：冠状动脉疾病患者冠状动脉循环中氧化低密度脂蛋白的评价及其与经皮冠状动脉介入的关联
5. The Benefit of an Intensive Primary Prevention Program for Cardiovascular Disease in Low Versus Moderate Risk Groups Based Upon the Coronary Artery Calcium Score [D] . Rubin, Abbey. 2019

机译：基于冠状动脉钙评分的低与中度风险群体的心血管疾病密集初级预防计划的益处
6. Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse cardiovascular events: A multicentre pilot study [O] . Zi-wen Zhao, Yi-wei Xu, Shu-mei Li, 2019

机译：一项稳定的冠状动脉疾病患者血清中较高的血清凝集素样氧化型低密度脂蛋白受体-1水平与重大不良心血管事件相关：一项多中心先导研究
7. Pro-Inflammatory Interleukin-1 Genotypes Potentiate the Risk of Coronary Artery Disease and Cardiovascular Events Mediated by Oxidized Phospholipids and Lipoprotein(a) [O] . Tsimikas Sotirios, Duff Gordon W., Berger Peter B., 2014

机译：促炎性白介素-1基因型增加了由氧化磷脂和脂蛋白介导的冠状动脉疾病和心血管事件的风险（a）

Pro-Inflammatory Interleukin-1 Genotypes Potentiate the Risk of Coronary Artery Disease and Cardiovascular Events Mediated by Oxidized Phospholipids and Lipoprotein (a)

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