The minus-end actin capping protein UNC-94/tropomodulin regulates development of the Caenorhabditis elegans intestine

摘要

BackgroundTropomodulins are actin capping proteins that regulate the stability of the slow growing, minus-ends of actin filaments. The C. elegans tropomodulin homolog, UNC-94 has sequence and functional similarity to vertebrate tropomodulins. We investigated the role of UNC-94 in C. elegans intestinal morphogenesis.