Validation of Disability Status a Claims-Based Measure of Functional Status for Cancer Treatment and Outcomes Studies

摘要

BackgroundIn prior research, we developed a claims-based prediction model for poor patient disability status (DS), a proxy measure for performance status, commonly used by oncologists to summarize patient functional status and assess ability of a patient to tolerate aggressive treatment. In this study, we implemented and validated the DS measure in 4 cohorts of cancer patients: early and advanced non-small cell lung cancers (NSCLC), stage IV estrogen-receptor (ER-) negative breast cancer, and myelodysplastic syndromes (MDS).