Piston versus Scissors: Chemotaxis Receptors versus Sensor His-KinaseReceptors in Two-Component Signaling Pathways

摘要

In this issue of Structure, Molnar and colleagues present a pair of important advances: (1) a method to analyze multiple signaling states in on-off switch proteins and (2) evidence for a scissors-type mechanism of on-off switching in a full-length, membrane-bound receptor of the sensor histidine-kinase class.