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Unraveling the nature of autism: finding order amid change

机译:揭示自闭症的本质:在变化中寻找秩序

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摘要

In this article, we hypothesize that individuals with autism spectrum disorder (ASD) are born with a deficit in invariance detection, which is a learning process whereby people and animals come to attend the relatively stable patterns or structural regularities in the changing stimulus array. This paper synthesizes a substantial body of research which suggests that a deficit in the domain-general perceptual learning process of invariant detection in ASD can lead to a cascade of consequences in different developmental domains. We will outline how this deficit in invariant detection can cause uncertainty, unpredictability, and a lack of control for individuals with ASD and how varying degrees of impairments in this learning process can account for the heterogeneity of the ASD phenotype. We also describe how differences in neural plasticity in ASD underlie the impairments in perceptual learning. The present account offers an alternative to prior theories and contributes to the challenge of understanding the developmental trajectories that result in the variety of autistic behaviors.
机译:在本文中,我们假设患有自闭症谱系障碍(ASD)的人天生具有不变性检测的缺陷,这是一个学习过程,在此过程中,人和动物开始参与变化的刺激阵列中相对稳定的模式或结构规律。本文综合了大量研究,这表明ASD中不变检测的领域一般感知学习过程中的缺陷可能导致在不同的开发领域中产生一系列后果。我们将概述不变检测中的这种缺陷如何导致ASD患者的不确定性,不可预测性和缺乏控制,以及在此学习过程中不同程度的损伤如何解释ASD表型的异质性。我们还描述了ASD中神经可塑性的差异是如何导致知觉学习障碍的。本报告为现有理论提供了一种替代方法,并有助于理解导致自闭症行为多种多样的发展轨迹。

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