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Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities

机译：骨关节炎中结合肝素的表皮生长因子样生长因子（HB-EGF）增加并调节软骨细胞的分解代谢和合成代谢活动

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摘要

ObjectiveWe determined if the epidermal growth factor receptor ligand HB-EGF is produced in cartilage and if it regulates chondrocyte anabolic or catabolic activity.

机译：目的我们确定表皮生长因子受体配体HB-EGF是否在软骨中产生，以及它是否调节软骨细胞的合成代谢或分解代谢活性。

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期刊名称 other
作者
D.L. Long; V. Ulici; S. Chubinskaya; R.F. Loeser;
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作者单位

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年(卷),期 -1(23),9
年度 -1
页码 1523–1531
总页数 19
原文格式 PDF
正文语种
中图分类
关键词
cartilage growth factors metalloproteinases integrins bone morphogenetic proteins chondrocytes;

机译：软骨;生长因子;金属蛋白酶;整联蛋白;骨形态发生蛋白;软骨细胞;

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专利

1. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities [J] . Long D. L., Ulici V., Chubinskaya S., Osteoarthritis and cartilage . 2015,第9期

机译：骨关节炎中结合肝素的表皮生长因子样生长因子（HB-EGF）增加并调节软骨细胞的分解代谢和合成代谢活动
2. Mice overexpressing the gene for heparin-binding epidermal growth factor-like growth factor (HB-EGF) have increased resistance to hemorrhagic shock and resuscitation. [J] . Zhang HY, Radulescu A, Chen CL, Surgery . 2011,第2期

机译：小鼠肝素结合表皮生长因子样生长因子（HB-EGF）基因的过表达增加了对失血性休克和复苏的抵抗力。
3. The cell-penetrating peptide domain from human heparin-binding epidermal growth factor-like growth factor (HB-EGF) has anti-inflammatory activity in vitro and in vivo [J] . LeeJ.-Y., SeoY.-N., ParkH.-J., Biochemical and Biophysical Research Communications . 2012,第4期

机译：人肝素结合表皮生长因子样生长因子（HB-EGF）的穿透细胞的肽域在体外和体内均具有抗炎活性
4. Bayesian Learning for Feed-Forward Neural Network with Application to Proteomic Data: The Glycosylation Sites Detection of the Epidermal Growth Factor-Like Proteins Associated with Cancer as a Case Study [C] . Alireza Shaneh, Gregory Butler Canadian Society for Computational Studies of Intelligence Conference(Canadian AI 2006); 20060607-09; Quebec City(CA) . 2006

机译：贝叶斯学习的前馈神经网络及其在蛋白质组学数据中的应用：与癌症相关的表皮生长因子样蛋白的糖基化位点检测
5. Mechanism of anabolic steroid stimulated bovine muscle growth: Role of the epidermal growth factor receptor [D] . Reiter, Brenda C. 2013

机译：合成代谢类固醇刺激牛肌肉生长的机制：表皮生长因子受体的作用
6. The metalloendopeptidase nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF). [O] . Véronique Hospital, Eiichiro Nishi, Michael Klagsbrun, 2002

机译：肝素结合表皮生长因子样生长因子（HB-EGF）可以有效抑制金属内肽酶Nardilysin（NRDc）。
7. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities [O] . Long D.L., Ulici V., Chubinskaya S., 2015

机译：骨关节炎中结合肝素的表皮生长因子样生长因子（HB-EGF）增加并调节软骨细胞的分解代谢和合成代谢活动
8. Epidermal Growth Factor-Like Ligands in Breast Cancer [R] . Adamson, E. D. 1998

机译：乳腺癌中的表皮生长因子样配体

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities

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