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Surgical Versus Conservative Treatments for Displaced Midshaft Clavicular Fractures

机译:移位性中轴锁骨骨折的外科手术和保守治疗

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摘要

Multiple meta-analyses have been performed to compare surgical and conservative interventions for treating displaced midshaft clavicular fractures. But conclusions are discordant.The purposes of current study were (1) to conduct a systematic review of meta-analyses comparing surgical and conservative interventions for the treatment of displaced midshaft clavicular fractures, (2) to help decision makers interpret and choose among discordant meta-analyses, and (3) to provide treatment recommendations through the best available evidence.We searched the Cochrane library, PubMed, and EMBASE databases to identify meta-analyses comparing surgical and conservative treatments for the displaced midshaft clavicular fractures. Two investigators independently scanned titles and abstracts to exclude irrelevant articles and identify meta-analyses that met the eligibility criteria. The methodological quality of the meta-analysis was independently assessed by the two investigators using the Oxford Centre for Evidence-based Medicine Levels of Evidence and the Assessment of Multiple Systematic Reviews (AMSTAR) tool. The Jadad decision algorithm was applied to determine which of the included studies provided the best available evidence.Six meta-analyses met the eligibility criteria in this systematic review. AMSTAR scores ranged from 5 to 10. The Jadad decision-making tool suggests that the highest quality review should be selected based on the publication characteristics of the primary trials, the methodology of the primary trials, the language restrictions, and whether analysis of data on individual patients was included in the study. As a result, we selected a high-quality Cochrane review.This systematic review of overlapping meta-analyses comparing surgical and conservative treatments suggests that surgical treatment provides a lower rate of overall treatment failure and a better functional outcome, but is associated with more implant-related complications. Hence, treatment should be individualized, with careful consideration of the advantages and disadvantages of each treatment method and of patient preferences.
机译:已经进行了多次荟萃分析,以比较手术和保守干预治疗移位的中轴锁骨骨折。但是结论是不一致的。本研究的目的是(1)对荟萃分析进行系统回顾,比较手术和保守治疗移位性中轴锁骨骨折的疗效,(2)帮助决策者解释和选择不一致的荟萃分析,以及(3)通过现有最佳证据提供治疗建议。我们在Cochrane库,PubMed和EMBASE数据库中进行了检索,以发现荟萃分析来比较移位和中枢性锁骨中段骨折的手术治疗与保守治疗。两名调查员独立扫描标题和摘要,以排除不相关的文章,并确定符合资格标准的荟萃分析。两位研究人员使用牛津循证医学证据中心的水平和多重系统评价评估(AMSTAR)工具独立评估了荟萃分析的方法学质量。应用Jadad决策算法确定纳入的哪些研究提供了最佳的证据。六项荟萃分析符合本系统评价的入选标准。 AMSTAR的分数介于5到10之间。Jadad决策工具建议应根据主要试验的发表特征,主要试验的方法,语言限制以及是否对数据进行分析来选择质量最高的综述个别患者包括在研究中。结果,我们选择了高质量的Cochrane评价。这项对手术和保守治疗进行比较的重叠荟萃分析的系统评价表明,手术治疗提供了较低的总体治疗失败率和更好的功能结果,但与更多的植入物相关相关的并发症。因此,应谨慎对待每种治疗方法,并仔细考虑每种治疗方法的优缺点以及患者的喜好。

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  • 作者

    Jia-Guo Zhao; Jia Wang; Lei Long;

  • 作者单位
  • 年(卷),期 -1(94),26
  • 年度 -1
  • 页码 e1057
  • 总页数 8
  • 原文格式 PDF
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