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Durability of Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir

机译：恩替卡韦或替诺福韦治疗的慢性乙型肝炎患者乙型肝炎抗原血清转换的持久性

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IntroductionLoss of HBeAg and development of anti-HBe (seroconversion) is seen as a milestone and endpoint in the treatment of HBeAg-positive patients with chronic hepatitis B (CHB). Among patients treated with nucleos (t)ide analogs (NA), recurrent viremia is common after discontinuation of therapy. Entecavir (ETV) and tenofovir (TDF) are highly potent NA. The durability of virological response and HBeAg seroconversion in patients treated with these agents is not well studied.

机译：简介HBeAg的丢失和抗HBe的发展（血清转化）被视为治疗慢性乙型肝炎（CHB）的HBeAg阳性患者的里程碑和终点。在接受核苷酸（t）ide类似物（NA）治疗的患者中，停药后复发病毒血症很常见。恩替卡韦（ETV）和替诺福韦（TDF）是非常有效的NA。在用这些药物治疗的患者中，病毒学应答和HBeAg血清转化的持久性尚未得到很好的研究。

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期刊名称 other
作者
Tse-Ling Fong; Andy Tien; Kahee J. Jo; Danny Chu; Eddie Cheung; Edward A. Mena; Quang-Quoc Phan; Andy S. Yu; Wafa Mohammed; Andrew Velasco; Vinh-Huy LeDuc; Nickolas Nguyen; Steven-Bui Han; Mimi Chang; Ho S. Bae; Yong-Won Cho; Myron J. Tong; Stewart L. Cooper;
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年(卷),期 -1(60),11
年度 -1
页码 3465–3472
总页数 14
原文格式 PDF
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关键词
Remission Relapse Seroreversion;

机译：缓解;复发;逆转;

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专利

1. Durability of Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir [J] . Fong Tse-Ling, Tien Andy, Jo Kahee J., Digestive Diseases and Sciences . 2015 ,第11期

机译：恩替卡韦或替诺福韦治疗的慢性乙型肝炎患者乙型肝炎抗原血清转换的持久性
2. Sequential Combination Therapy with Pegylated Interferon Leads to Loss of Hepatitis B Surface Antigen and Hepatitis B e Antigen (HBeAg) Seroconversion in HBeAg-Positive Chronic Hepatitis B Patients Receiving Long-Term Entecavir Treatment [J] . Li Guo-Jun, Yu Yi-Qi, Chen Shao-Long, Antimicrobial agents and chemotherapy. . 2015 ,第7期

机译：长期接受恩替卡韦治疗的HBeAg阳性慢性乙型肝炎患者序贯联合治疗与聚乙二醇化干扰素会导致乙型肝炎表面抗原和乙型肝炎e抗原（HBeAg）血清转换丧失
3. Seroconversion of Hepatitis B Virus Surface Antigen in Chronic Hepatitis B Child Treated with Entecavir [J] . Dong Li, Junping Wang, Junqing Zhou, North American Journal of Medical Sciences . 2012 ,第9期

机译：恩替卡韦治疗慢性乙型肝炎儿童的乙型肝炎病毒表面抗原的血清转化
4. Genotype and Serotype Identification of Hepatitis B Virus in Chronic Hepatitis B Patients Treated with Telbivudine [C] . Y Purnamasari, Tien, Arimaswati, International Seminar on Smart Molecule of Natural Resources . 2020

机译：临床治疗慢性乙型肝炎患者乙型肝炎病毒的基因型和血清型鉴定
5. Incidence, Durability, and Clinical Outcomes of Hepatitis B Surface Antigen Seroclearance in Patients with Chronic Hepatitis B [D] . Yip, Cheuk Fung. 2019

机译：慢性乙型肝炎患者乙型肝炎表面抗原血管疮的发病率，耐久性和临床结果
6. Sequential Combination Therapy with Pegylated Interferon Leads to Loss of Hepatitis B Surface Antigen and Hepatitis B e Antigen (HBeAg) Seroconversion in HBeAg-Positive Chronic Hepatitis B Patients Receiving Long-Term Entecavir Treatment [O] . Guo-Jun Li, Yi-Qi Yu, Shao-Long Chen, 2015

机译：长期接受恩替卡韦治疗的HBeAg阳性慢性乙型肝炎患者序贯联合治疗与聚乙二醇化干扰素会导致乙型肝炎表面抗原和乙型肝炎e抗原（HBeAg）血清转换丧失
7. Hepatitis B surface antigen quantification at hepatitis B e antigen seroconversion predicts virological relapse after the cessation of entecavir treatment in hepatitis B e antigen-positive patients [O] . Yuan-wang Qiu, Li-hua Huang, Wen-long Yang, 2016

机译：乙型肝炎e抗原血清学转换的乙型肝炎表面抗原定量预测乙型肝炎e抗原阳性患者停用恩替卡韦后病毒学复发

Durability of Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir

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