A Hamster-Derived West Nile Virus Isolate Induces Persistent Renal Infection in Mice

摘要

BackgroundWest Nile virus (WNV) can persist long term in the brain and kidney tissues of humans, non-human primates, and hamsters. In this study, mice were infected with WNV strain H8912, previously cultured from the urine of a persistently infected hamster, to determine its pathogenesis in a murine host.