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Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone

机译:结合多剂量甲氨蝶呤和米非司酮的可行胚胎剖宫产瘢痕的新疗法

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摘要

An ectopic pregnancy is defined as cesarean scar pregnancy (CSP) when the products of conception are implanted within the myometrium in the area of a cesarean section scar. CSP can be a life-threatening condition and to date there is no clear consensus for CSP management. A medical approach joining high treatment rates with fertility preservation could be a safer and less invasive method of therapy.We present a case of CSP with a viable embryo that was successfully treated with a novel medical therapy combining multidose methotrexate (MTX) and mifepristone.No further additional invasive procedure was required since pregnancy products were dissolved and no major complications were experienced.Multidose MTX and mifepristone can be considered a safe and effective treatment for CSP.
机译:当将受孕产物植入剖宫产疤痕区域的子宫肌层内时,异位妊娠被定义为剖宫产疤痕妊娠(CSP)。 CSP可能会危及生命,迄今为止,CSP管理尚无明确共识。结合高治疗率和生育力的医学方法可能是一种更安全,侵入性更小的治疗方法。我们介绍了一个CSP病例,该病例具有活的胚胎,已成功通过多剂量甲氨蝶呤(MTX)和米非司酮的新型药物疗法成功治疗。由于妊娠产物已溶解且未经历重大并发症,因此需要进一步的侵入性手术。多剂量MTX和米非司酮可以被认为是安全有效的CSP治疗方法。

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