Donor Hepatic Steatosis Induce Exacerbated Ischemia-Reperfusion Injury through Activation of Innate Immune Response Molecular Pathways

摘要

BackgroundSevere liver steatosis is a known risk factor for increased ischemia-reperfusion injury (IRI) and poor outcomes post liver transplantation (LT). This study aimed to identify steatosis-related molecular mechanisms associated with IRI exacerbation post-LT.