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Ultrananocrystalline Diamond Integration with Pyrolytic Carbon Components of Mechanical Heart Valves

机译:超纳米晶金刚石与机械心脏瓣膜的热解碳组分集成

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摘要

In this report, an idea of integrating ultrananocrystalline diamond (UNCD) with pyrolytic carbon (PyC) –based mechanical heart valves, has been demonstrated. The report addresses the strategies to avoid graphitization and film delamination during the diamond coating. Raman and scratch tests showed that a UNCD film with high purity could adhere to the PyC substrate strongly. A thrombin generation study demonstrated an excellent biocompatibility of UNCD towards fresh human platelets. These results suggest that UNCD could be a good candidate of surface material for next generation heart valves and other implantable devices.
机译:在本报告中,已经证明了将超纳米晶金刚石(UNCD)与基于热解碳(PyC)的机械心脏瓣膜整合的想法。该报告阐述了在金刚石涂层过程中避免石墨化和薄膜分层的策略。拉曼和划痕测试表明,高纯度的UNCD膜可以牢固地粘附在PyC基材上。凝血酶生成研究证明了UNCD对新鲜人类血小板具有极好的生物相容性。这些结果表明,UNCD可能是下一代心脏瓣膜和其他可植入设备的表面材料的良好选择。

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