Cytopathological evaluation of ocular surface and needle washings following intravitreal melphalan injections for retinoblastoma

摘要

There is concern that injections into retinoblastoma eyes are dangerous and allow tumor escapement. This study evaluated 200 ocular surface and 202 needle washings obtained from 280 injections into retinoblastoma eyes. With this injection and evaluation technique, no malignant cells were recovered, highlighting the low risk of the procedure.